Methylhexaneamine (1, 3-dimethylamylamine) – UPDATE

Methylhexaneamine (1, 3-dimethylamylamine) – Why this is now a problem.

We previously covered the topic 1, 3, Dimethylamyaline (Geranium Oil) back in September of 2010; after receiving an alarming number of emails and responses from clients and followers on various social media websites.    We thought it would be a good idea to address some of your questions. 


What is Methylhexaneamine?
Methylhexaneamine is a weak stimulant that was first trademarked under the name ‘Forthane’ by Eli Lilly in April of 1971 as a nasal decongestant.  The trademark has long expired, but Methylhexaneamine has continued to grow in popularity over the years.


Why is Methylhexaneamine banned by some sport organizations?
Methylhexaneamine is considered a stimulant; most sport governing bodies around the world consider most stimulants to be banned, including Methylhexaneamine.

I’ve asked about a particular product in the past and it was fine, so why is it banned now?
In 1994, the Dietary Supplement Health and Education Act (DSHEA) passed into law and radically changed the dietary supplement marketplace.  DSHEA expanded the category of dietary supplements further to include:

·                Ginseng

·                Fish oils

·                Enzymes

·                DHEA and more

 DSHEA removed much of the FDA's control over dietary supplements and as a result created what is considered to be a virtually unregulated industry.  Some supplement products change frequently (quarterly, yearly, etc…), others are forced to change because of market recalls.  This uncertainty is why we must continue to check dietary supplement ingredients, because last year’s formula could be obsolete and the new product could include ingredients banned for athletes.

I did not see Methylhexaneamine listed as an ingredient, could it be listed as something else?

Yes.  Here are the most common names (synonyms) that we have seen listed in dietary supplements; if you come across any of these names in an ingredients list, I advise you to not consume.

1, 3-dimethylamylamine (Most common – This is updated from the September blog)

·         Geranium oil extract

·         Geranuim oil

·         Geranium extract

·         Geranamine (trademarked by Proviant Technologies)

·         Methylhexanamine

·         DMAA

·         Forthane

·         Forthan

·         Floradrene

·         4-methyl-2-hexanamine

·         4-Methylhexan-2-amine

·         2-amino-4-methylhexane

·         2-hexanamine, 4-methyl-

·         2-hexanamine, 4-methyl- (9CI)

·         1,3-dimethylamylamine

·         1,3-dimethylpentylamine

·         Pentylamine, 1, 3-dimethyl-

So should I be worried if the label only lists Geranium oil and no other synonyms?

Yes, Geranium oil (extract) is often used in place of Methylhexaneamine or 1, 3-dimethylamylamine because the general public views Geranium oil to be a ‘natural’ substance and thus ‘safe’.  Geranium is a nonessential trace element that has caused nephrotoxicity (kidney injury) and death when used chronically by humans, even at recommended levels of use.

What products do you commonly find these ingredients listed in?

The most common product that we receive questions on still remains to be Jack3d by USP Labs.  Jack3d, lists, [1, 3 Dimethylamylamine] and caffeine.  The following is a list of the top 10 product names, manufacture and banned (problematic) ingredients as listed on the label, in order of most popular.

1.           Jack3d – USPlabs (1,3 Dimethylamylamine (Geranium [Stem], caffeine)

2.           OxyELITE Pro – USPlabs (1,3 Dimethylamylamine(Geranium [Stem], caffeine)

3.           Hemo-Rage Black Ultra Concentrate – Nutrex (1,3 Dimethylamylamine)

4.           C4 Extreme - Cellucor (1,3 Dimethylamylamine HCI, caffeine)

5.           Rezolution – LG Sciences (1,3 Dimethylamylamine (Geranium Flower), Bitter Orange (synephrine), caffeine)

6.           Liquid Clenbutrx Hardcore – VPX (Apple Geranium (Pelargonium Odorantissomum) (Leaves) [Std. To 1,3-Dimethylpentylamine],caffeine)

7.           Heat Accelerated – Magnum Nutraceuticals (Geranium Oil Extract, Citrus Aurantium, caffeine)

8.           CryoShock – Neogenix (1,3 Dimethylamylamine, caffeine)

9.           RedLine Black On Blue V2 – VPX (Supra-Amine™ Apple Geranium (Pelargonium Odoratissimum) (Leaves) [Std. To 1,3-Dimethylpentylamine], caffeine)

10.       Motivate – Anabolic Innovations (1,3 Dimethylamylamine, caffeine)

Have you seen reports of individuals failing drug test because of Methylhexaneamine?

Yes, we have seen positive drug test in regards to Methylhexaneamine, and the numbers seem to be rising.  If you are using any of these supplements, please be aware that the presence of Methylhexaneamine will cause a positive drug test.

Please be advised that supplement use can be dangerous to your health and your eligibility.  The REC does not recommend the use of any dietary supplement and encourages athletes to turn to food first for their dietary needs. Athletes must remember that you are always 100% responsible for what you consume.