Weight-Loss Supplements: Warnings for Athletes

Contributed by: Anna Filardo, Education Program Manager, Drug Free Sport

As summer approaches, there has been an increase in weight-loss/thermogenic supplement (WLT) inquiries in Drug Free Sport AXIS™.  These types of supplements come with increased risks and dangers to athlete health and safety. It is important for athletes to know the risks associated with taking any dietary supplement. Lacking regulation by the U.S. Food and Drug Administration (FDA), the FDA does not review or test supplements before they are available for consumer purchase. Read on to learn more about the dangers associated with WLT supplements.

One of the Top Three Supplement Categories Recalled by the FDA ⁽¹⁾

WLT supplements are regularly recalled by the FDA, due to undeclared pharmaceutical ingredients present in the bottle. Recalled WLT products often contain sibutramine (an ingredient found in a drug called Meridia), which was removed from the market in October 2010 by the FDA due to causing heart problems and strokes ⁽²⁾. Not only can products with undeclared pharmaceutical ingredients cause a positive drug test, but they can also create serious harm to the body.

Often Contain Banned Stimulants ⁽³⁾

WLT supplements often list ingredients that are banned under the “Stimulants” drug class by sport organizations. Look out for synephrine, AMP citrate, bitter orange, ephedra, hordenine, in particular. These ingredients are likely to cause a positive drug test in most sports organizations testing for performance-enhancing substances. Athletes may also experience adverse health effects from taking these stimulants, especially when they are combined into one product formula, or consumed with energy drinks and other secondary stimulant sources.

Harmful and Dangerous Side-Effects ⁽³⁾

Users may experience harmful or dangerous side-effects after taking a weight-loss/thermogenic supplement. Side-effects users have experienced when taking these supplements include liver failure, anxiety, nervousness, increased blood pressure and heart rate, chest pain, and heart attacks⁽⁴⁾. Additionally, these products have been cited to react adversely to prescription medications by increasing or minimizing the prescription drug’s intended effect. ⁽⁵⁾

Product Marketing Often Contains False Claims ⁽²⁾

Dietary supplements are not tested for efficacy or safety; therefore, many claims made by dietary supplements are false and not proven by reliable scientific research. Beware of products making claims such as “promotes weight loss,” “scientific breakthrough,” “incinerates fat,” and “significantly reduces BMI.” These claims are often unsubstantiated and may cause more issues than assistance.

Solution: Use Nutrition to Reach Weight-Loss Goals

Eating whole foods, following a balanced eating plan, and getting regular physical activity is the best and most effective way to lose and maintain weight. Athletes are recommended to work with a sports dietitian to evaluate their meal plan and find the best solution to reach their weight-loss and performance goals. Check out Drug Free Sport AXIS™ for athlete-friendly recipes in our Athlete Recipe Box.

Bottom Line: WLT supplements are commonly contaminated or adulterated, may cause adverse health effects, and are not as effective as a balanced meal plan accompanied with regular exercise.

Learn more about dietary supplement safety by viewing our short video on YouTube.

Athletes that are part of subscribing member organizations can have your dietary supplement(s) reviewed by submitting a dietary supplement inquiry on Drug Free Sport AXIS.

References:

• U.S. Food & Drug Administration, Tainted Products Marketed as Dietary Supplements
• U.S. Food & Drug Administration, Beware of Products Promising Miracle Weight Loss
• National Institute of Health, Office of Dietary Supplements, Dietary Supplements for Weight Loss
• Livestrong.com, How do Thermogenic Fat Burners Work?
• U.S. Food & Drug Administration, Mixing Medications and Dietary Supplements Can Endanger Your Health

Amphetamine Misuse For Academic Gain: How Effective Are They?

Contributed by Anna Filardo, Education Program Manager at Drug Free Sport, Inc.

More NCAA student-athletes report using ADHD medications without a prescription compared to those with a prescription and medical diagnosis, according to the 2014 NCAA Substance Abuse Survey. Especially around this time of year, students may misuse or abuse prescription amphetamines such as Adderall, Ritalin, and Concerta to enhance memory and academic performance.

This is of concern to a number of sports organizations as not only are amphetamines banned/prohibited, but also potentially harmful to the athlete’s health. And ultimately, if the athlete does not have attention deficit/hyperactivity disorder (ADHD), does the non-medical use of these prescription stimulants actually lead to improved academic outcomes? We decided to investigate. 

Results from the NCAA Substance Abuse Survey.

First, let’s get a few knowledge points out of the way.

Amphetamines are:

• Occasionally called “speed” or “uppers," are synthetic, psychoactive drugs that are central nervous system (CNS) stimulants. 
• Prescribed to treat narcolepsy, obesity, and attention deficit/hypertension disorder (ADHD). 
• Considered performance-enhancing drugs (PEDs) that delay the onset of (or mitigate) fatigue. 
• Banned/prohibited stimulants by most, if not all, sports organizations. 
• Commonly found in dietary supplements, namely those marketed as “pre-workouts," but also hidden in other types of supplements. 
• Listed on product labels under different names or chemical formulas, causing uncertainty for consumers. (See Box 1 for examples popular ingredients of concern.) 
• Associated with negative health effects when misused/abused. (See Box 2.)

But, are they effective for improved academic performance?

In 2015, researchers from the University of Pennsylvania found that ADHD medications provide little to no benefit to those without medical need. In fact, the medication caused a decrease in motivation, and an increase in omission errors when compared to a control group. Amphetamine-users also perceived themselves as having poorer study habits and lower motivation than their non-user counterparts.

The University of Maryland School of Public Health conducted a literature review on non-medical amphetamine use among college-aged students. Their research revealed that non-medical use of amphetamines was also associated with the following characteristics in college-aged students:

• Excessive drinking and other drug use 
• Lower GPA 
• Low perceived harmfulness of using prescription stimulants non-medically 
• Greater attention difficulties 
• Psychiatric distress or depressed mood 
• More likely to skip class 
• Affiliation with a Greek (fraternity/sorority) organization 

For the full University of Maryland report click here: Nonmedical Use of Prescription Stimulants.

Medical Exceptions for ADHD Medications

The NCAA and World Anti-Doping Association (WADA) do have medical exception processes that athletes may complete should prescription amphetamines be required for a diagnosed medical need. NCAA and WADA athletes will need to fill out the ADHD Medical Exception Reporting Form or the Therapeutic Use Exemptions (TUE) form, respectively. The use of amphetamines will cause a positive drug test—and without a current prescription and medical exception, appropriate sanctions will follow.

Amphetamines are more dangerous than perceived and should only be used under the direction of a medical doctor. Prescription amphetamines are Schedule II drugs with considerable potential for abuse and addiction. According to the Drug Enforcement Agency, distributing Schedule II stimulants illegally (e.g., sharing or selling pills) is a felony.

If you or a student-athlete have a questions regarding amphetamine use (dietary supplement or medication), please visit www.dfsrec.com or call Drug Free Sport at 877-202-0769.



References:
Center for Substance Abuse Research. (2013, Oct. 29). Amphetamines Retrieved from http://www.cesar.umd.edu/cesar/drugs/amphetamines.asp
Center on Young Adult Heath and Development, University of Maryland School of Public Health. Retrieved from http://medicineabuseproject.org/assets/documents/NPSFactSheet.pdf
Illeva, I.P., & Farrah, M.J. (2015). Attention, motivation, and study habits in users of unprescribed ADHD medication. Journal of Attention Disorders, 1-13. doi: 10.1177/1087054715591849
Lakhan, S.E., & Kirchgessner, A. (2012). Prescription stimulants in individuals with and without attention deficit hyperactivity disorder: misuse, cognitive impact, and adverse effects. Brain and Behavior
National Collegiate Athletic Association. (2013). [Graph illustration from NCAA substance use survey]. NCAA National Study of Substance Use Habits of College Student-Athletes. Retrieved from https://www.ncaa.org/sites/default/files/Substance%20Use%20Final%20Report_FINAL.pdf
Rosenbloom, C.A., & Coleman, E.J. (2012). Sports Nutrition: A practice manual for professionals. United States of America: Academy of Nutrition and Dietetics.