Drug Free Sport Staff Writers

Drug Free Sport Staff Writers
Showing posts with label human growth hormone. Show all posts
Showing posts with label human growth hormone. Show all posts

Monday, February 6, 2017

Drug Free Sport Staff Weigh-in on Industry Trends Leading Into 2017

Contributed by Lara Gray, Director of Education


For this week’s blog, we interviewed a few of the staff at Drug Free Sport. We asked them to share insights from drug testing in 2016, and potential new (or repeating) trends in 2017.


LG: What, if anything, is changing in sport drug testing and analysis?
Staff: More and more, we are seeing professional sport leagues test blood samples as well as urine to ensure fair play. Amateur and institutional clients are beginning to look into oral fluid testing and other matrices as complementary features of their current drug testing program.


LG: Specific to the blood testing, what’s changing?
Staff: The World Anti-Doping Association (WADA) has validated Human Growth Hormone (hGH) biomarker analysis to compliement isoform testing for hGH. Essentially, they’re able to test for a greater detection window with the biomarker analysis that can show hGH up to two weeks after administration. Comparatively, isoform testing can detect hGH only within 24 – 48 hours of administration.


LG:  Is WADA validation important with new testing methods?
Staff: Of course. Many sport leagues look to the WADA Code and Prohibited Substances List as a gold standard. However, full implementation of WADA protocols can be difficult for clients that must also negotiate terms with their players unions through Collective Bargaining Agreements.


LG: What are sport organizations doing to work with the players unions and still provide effective drug testing programming?
Staff: “Smart” testing is becoming a new trend where we are seeing a shift to testing methodologies that efficiently and effectively use appropriate funds for deterrence testing. We are seeing this across the board for professional, amateur, and collegiate/institutional clients. Essentially, everyone is learning how to make the most of their drug-testing dollars and amplify the impact on deterrence.


LG: Are there any changes being made to the substances tested for in sport?
Staff: Nothing is changing dramatically in terms of the substances screened, even with marijuana which gets a lot of attention. We don’t anticipate any significant changes in marijuana testing as a result of the legislation efforts in several states across the country. Until there is a change from the Federal government, there likely won’t be a change in marijuana as a banned substance in sport. What has changed, however, is the conversation around marijuana—again, because of legalization in certain states.



LG: Can you elaborate? What has changed in the conversation?
Staff: There is a discussion targeting the social acceptability of marijuana—especially in the states where it is now legal for recreational use. We are providing more education on the different forms of marijuana use like edibles and concentrates, or that athletes may be using e-cigarettes or vape pens to mask their use on campus or within the sports facility. The potency of marijuana has changed dramatically over the last few years, which may be leading to higher dosages, longer lasting effects in the body, even addiction. For institutional collegiate clients, marijuana remains the largest concern on campuses.


LG: Are there other substances of concern looking ahead into 2017?
Staff: It’s hard to say what will be new in 2017, but there is growing concern over growth hormone releasing peptides (GHRPs) in professional sports, and the reemergence of anabolic steroids that were popular in the Eighties. SARMs, such as ostarine and LGD-4033, are also a concern as they are appearing in more supplement items and marketed as “legal”, which is absolutely false. Collegiately, there have been increasing requests for testing panels to include prescription narcotics and opiates. Prescription stimulants being used and abused without a prescription are also concerns on college campuses—we’ve even heard stories specific to athletes snorting amphetamines like Adderall.


LG: Sounds like there’s a lot going on! Are there any other trends you feel are important to share?
Staff: Probably the technology that surrounds drug-testing and third party administration of programs. For example, there are a number of researchers working on new technology that can detect certain drugs at lower specific gravity (or urine concentrations). Labs are also making strides to update machines that are “greener” in terms of efficiency. This helps decrease the turnaround time for receiving results which positively benefits the clients. We also know that there is a lot of work going into delivering appropriate protocols for testing transgender athletes. In January, we distributed our "Collection Procedures and Guidelines for Transgender Student-Athletes" to all of our collectors nationwide.


LG: Lastly, what impact (if any) do you feel the 2016 Russia doping issue has had on drug testing efforts in the US, or for Drug Free Sport specifically?
Staff: The impact is really just the importance of having independent administrators for drug-testing programs. A complete third-party that conducts athlete selection, administration of the program, conducts testing and works with WADA accredited labs, and provides accurate reports to the sport organization is critical. Their involvement must be completely separate and independently run. The Russia issues also increased the importance of consistency in communicating confidentiality and the code of ethics for drug testing to all of our certified collectors. Cyber security also becomes a larger concern in the wake of 2016.


LG: I think all of this is important to share and continue to discuss as we get further into 2017. Thanks for your time and insights!


For more information on any of the issues or topics discussed here, please email Lara Gray at lgray@drugfreesport.com.


Special thanks to the following staff members for their time and responses that made this blog possible: Ryan Willis, Sarah Ziegelmann, Allison Lathim, Ben Mosier, and Michaela Stemmons. 

Thursday, March 3, 2016

Blood Testing for Prohibited Substances in Sport

Welcome to the restored Drug Free Sport Blog, Perspectives

After a three-year hiatus, we are eager to begin sharing our expertise, stories, and trending news related to sport drug testing and athlete health. We hope to reengage our followers and expand our reach to new audiences to provide valuable “perspectives” about our company, staff, and the sport drug testing industry. Thank you for reading and sharing!

To kick-off our reentry into the blogosphere, we explore blood testing for prohibited substances in sport, current trends related to phlebotomy testing, and other fun facts from the industry.

To gain insight into the use of blood for drug testing athletes we sat down for a Q&A with our own Ben Mosier, Director of Professional Sports Drug Testing, Ryan Willis, Director of NFL PED Drug Testing, and Sarah Ziegelmann, Phlebotomy Services Program Manager.



Q: Drug Free Sport has been conducting blood drug testing in professional sports since 2004. Has anything significant changed in this area of drug testing?

A: Blood testing continues to expand in professional sports through the continuous addition of certified phlebotomists and an increased understanding of the process and specificity of testing. Currently, there is increasing interest in blood biomarkers and the athlete’s biological passport. Biomarker testing serves to monitor variables over time that may reveal the effect of doping, and the biological passport uses longitudinal profiling to test an athlete’s blood for initial testosterone levels. These levels are held on a file and reviewed in the future to determine if the athlete has used testosterone boosting substances. The World Anti-Doping Agency (WADA) will begin biomarker testing in the near future.

Q: So instead of testing for testosterone at a single test, you’re comparing the athlete’s own blood levels of testosterone from one sample to another over a period of time?

A:  Exactly. That would be an example of using the Athlete Biological Passport. The Athlete Biological Passport (ABP) provides a longitudinal study that monitors a panel of biomarkers within the athlete’s blood that will indirectly show the effects of doping over a period of time. Instead of searching for a specific performance-enhancing substance, a positive test can result from inconsistencies measured in the athlete’s biomarker levels. This is called a Non-Analytical Positive. Blood testing in sport can also identify and accurately detect two other categories of performance enhancement that other matrices cannot: Blood Doping and Human Growth Hormone (hGH).  

Q: Tell us about these other categories. What makes them different?

A:  There are several substances or methods used for blood doping in sports. Erythropoiesis Stimulating Agents (ESA), also known as recombinant erythropoietin (rEPO),work by stimulating the production of more red blood cells. Hemoglobin-based Oxygen Carriers (HBOC) and Homologous Blood Transfusions (HBT) are other blood doping methods. All three methods are used in various manners to increase an athlete’s red blood cell count, resulting in an increase of stamina and performance. Blood passport testing is used to target and identify these different doping methodologies. 

Human growth hormone (hGH) is a naturally occurring substance in the body produced by the pituitary gland. hGH is most often attributed to blood drug testing in sports. Synthetic hGH is used as a Performance Enhancing Drug (PED) to enhance the growth of bone, muscle and organ tissues within the body.  The Isoforms Test and Biomarkers Test can be used to determine whether the hGH levels in an athlete are naturally occurring or synthetically altered.



Q: How accurate are the results of these blood tests?

A: When conducted according to the specified collection procedures and protocols, blood testing provides less than a 0.01% error—higher accuracy than provided by urine drug tests.

Q: Are blood test results produced quicker than urine tests?

A: The speed of receiving results from a blood test is primarily dependent on the drug-testing laboratories’ volume at the time. The average timeframe for a result is 10 – 14 days, but for an additional fee the process can be expedited. A benefit of blood testing is the ability to test 20 samples at a time which can speed the process compared to urine testing. Urine testing has a 14 day result turn around.  

Q: How do athletes feel about blood testing compared to urine testing?

A: The average blood draw takes about 10 minutes, which most athletes prefer due to the quickness of the test and the ability to perform a test on demand as opposed to waiting to produce and validate a urine sample. On the other hand, some athletes have a fear of needles, making this type of testing less desirable. Under most circumstances, trained phlebotomists administering the tests are skilled at calming the athlete and successfully collecting a sample.

Q: What would be good information for athletes to know about what to expect from a blood test?


The average blood draw takes 10 minutes, 
and collects 10mL of blood.


10mL is one-third of a standard shot of espresso. 
Photo credit: by Sandstein (Own work) [CC BY 3.0 (http://creativecommons.org/licenses/by/3.0)], via Wikimedia Commons 


A: Well, the notification of a blood test to an athlete is dependent on if the sport is in-season or off-season. Also, to ensure accuracy, blood tests require specific amounts of time between when an athlete last engaged in physical activity/exercise and the blood collection. When being tested for hGH, the athlete must wait at least 30 minutes after exercise to produce a blood sample. For ESA blood testing, the athlete has to wait a minimum of two hours after engaging in physical activity.

Similar to urine-based drug tests, the athletes are able to select their testing devices and custody and control forms for testing. Trained phlebotomists ensure that clients have a full scope of knowledge in regards to the blood collection process; this also protects the health and safety of the athletes. Prior to testing, the phlebotomist will ask about the athlete’s history with providing blood samples along with potential complications. Once athlete identification and demographic information is confirmed, the blood draw begins. Blood tests are administered using a small needle and collect 10 milliliters (mL) of blood in a test tube. (Consider: The human body has approximately 5,500 mL of blood and a standard shot of espressoholds 30 mL of fluid.) The collection tube is then secured into transport kits, stored, and shipped in temperature controlled containers. Both the athlete and collector confirm the validity of the procedure with affidavits and if feeling well, the athlete is dismissed.



Blood testing collections continue to expand in professional sports and new scientific advancements and innovations further protect the integrity and landscape of the sport drug testing industry. Drug Free Sport oversees the collection of 5,000 blood tests annually. Our experts are here to answer questions and assist you through the process. Feel free to leave comments or reach out to us directly with any questions.